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Transfert d'embryons congelés

Transfert d'embryons congelés

  • Frozen embryo transfer is one of ART techniques. Basically, it is an in-vitro fertilization program minus the stimulation stage. This technique is advisable when the IVF protocol for some reason was unsuccessful. By preserving the embryos, the parents receive a kind of moral support boost, because even if the first try fails, there is always a second chance. Besides, it will be easier and a lot cheaper. 

    Many couples choose to tray frozen embryo transfer program after a successful IVF attempt to have a second baby. 

    The end result of this technique depends on various factors which include:

    • The quality of the frozen embryo
    • The endometrial thickness and if it is ready for the embryo transfer
    • The hormonal therapy strategy.

    Some scientists claim that the high dosage of hormones that women are injected with during the stimulation can alter the qualities of their endometrium and may have negative effect on its ability to accept and nourish the embryo. 

    If the patients use the frozen embryo transfer program, there is no need to do take hormones in such high doses, which makes this program closer to the natural way of things. Consequently, the pregnancy is likely to go more smoothly from the physiological point of view. 

    Is it necessary for the father to do a medical check-up with this protocol? Yes, it is. Even though he is not actually involved in the process of the transfer and has done the required tests during the first cycle, the frozen embryo transfer recommendations list does contain several obligatory examinations. As for the mother, out of all the usual hormone level exams she only has to do the progesterone blood test, because this hormone is prescribed to ensure a healthy pregnancy. 

    Sometimes, though fairly rarely, the usual superovulation stimulation protocol is still required to prepare the endometrium for the transfer. This happens when there is no natural ovulation and if the standard preparatory procedures yielded no results. 

    Regardless of their education level, many people still consider embryo cryopreservation a dangerous procedure that has the potential to harm their future baby. Sometimes, it may be hard for the parents to understand this process. These couples would rather dispose of their spare embryos, which is completely unnecessary and unfounded, just because they are afraid to freeze it. 

    However, it is essential to realize the difference between a common freezing and cryopreservation. When you freeze something the usual way, the water in the issues crystalizes under the influence of low temperatures and destroys the cell membranes. Cryopreservation in liquid nitrogen happens at the ultra-low temperature of -196 С°. Under these conditions, the ice simply does not have enough time to form. After they are defrosted, more than a half of all embryos can be successfully implanted into the womb tissue and start developing there. Out of 100 frozen embryos, only 5 or 6 of them are lost. Studies have proved that in those cases the cause of death is not related to cryopreservation, but is normally of genetic origin. Large-scale case studies have also demonstrated, that children born from frozen embryos are not any different from other children in terms of general health and course of development, and the pregnancy is usually less problematic. It might be connected to lower amount emotional stress for the parents. 

    Frozen embryos can be preserved for a very long time. An additional prove to that is the birth of a girl named Emma in 2017. Her embryo has been cryopreserved for 25 years, since 1992. The only condition is to strictly abide by the rules of cryopreservation and defrosting procedures. 

    In Altravita we use various ART techniques. Thanks to high-level equipment and the skills of our doctors, we keep our statistic results up to the highest standards. You can get more information about cryopreservation from our gynecologists. Call the clinic using the phone number on our website and make an appointment.

    Call the clinic using the phone number on our website and make an appointment.

Cryobanque

Cryobanque

Le diagnostic génétique préimplantatoire

Le diagnostic génétique préimplantatoire

  • PGD

    Pre-implantation genetic diagnosis (PGD) refers to genetic profiling of embryos created through IVF prior to the transfer into the patient’s uterus. During PGD the embryos are screened for a number of specific genetic disorders, so as to exclude the possibility of selected embryos having these particular abnormalities.

    PGD enables patients with a chronic disease in their family history to avoid passing it on to their children. A specialist may recommend PGD if patients have a family history of severe genetic diseases or previous miscarriages due to genetic disorders.

    PGS

    The term preimplantation genetic screening (PGS) is used to denote procedures that do not look for a specific disease but use PGD techniques to identify embryos at risk. PGS involves checking the embryos chromosomes for common abnormalities. Chromosomal abnormalities are a major cause of miscarriages and the failure of embryos to implant. They can also cause such serious medical conditions as Down’s syndrome.

    PGS is normally recommended for:

    • older patients ( women over 35 years old);
    • patients with a history of recurrent miscarriages;
    • patients with a history of unsuccessful IVF cycles after the embryo transfer stage;
    • patients with a family history of chromosomal diseases.
Maternité de substitution

Maternité de substitution

  • Surrogacy is an arrangement, often supported by a legal agreement, whereby a woman (the surrogate mother) agrees to bear a child for another person or persons, who will become the child's parent(s) after birth.

    The legal conditions and social attitude towards surrogacy in Russia are extremely positive; moreover, the program is able to help couples from the countries where surrogacy is prohibited or it is extremely expensive to become parents.

Soins prénatals

Soins prénatals

    • Suivi de la grossesse singleton trimestre I
    • Suivi de la grossesse singleton trimestre II
    • Suivi de la grossesse singleton trimestre III
    • Suivi de la grossesse singleton après la FIV trimestre I
    • Suivi de la grossesse singleton après la FIV trimestre II
    • Suivi de la grossesse singleton après la FIV trimestre III
    • Surveillance de grossesse multiple, incl. grossesse après la FIV trimestre I
    • Surveillance de grossesse multiple, incl. grossesse après la FIV trimestre II
    • Surveillance de grossesse multiple, incl. grossesse après la FIV trimestre III
    • Test de fuite de liquide amniotique «Frautest Amnio Al-Sense»
    • Consultation initiale d'un obstétricien-gynécologue jusqu'à 12 semaines
    • Consultation initiale d'un obstétricien-gynécologue sur le suivi de la grossesse à partir de 13 semaines après la FIV 
    • Consultation initiale d'un obstétricien-gynécologue sur le suivi de la grossesse
    • Test de base prénatal «Panorama» non invasif (Natera)
    • Test de fuite de liquide amniotique «Amnisure» (USA)
    • Test élargi prénatal «Panorama» non invasif (Natera)
Stimulation ovarienne

Stimulation ovarienne

Cultivation embryonnaire

Cultivation embryonnaire

Diagnostic d'infertilité  féminine

Diagnostic d'infertilité féminine

  • Ceux-ci comprennent: 

    • l'analyse du sang et de l'urine, la détermination du groupe 
    • sanguin et de son facteur Rh, l'analyse de la syphilis et 
    • de l'hépatite, ainsi que certains types d'infections virales.
Éclosion assistée

Éclosion assistée

Évaluation de la fusée  mitotique de la division  des œufs

Évaluation de la fusée mitotique de la division des œufs

  • Grâce au développement des technologies optiques et informatiques, il est devenu possible d'observer la fusée mitotique de la division en temps réel dans un œuf vivant.

    Un appareil appelé Poloscope vous permet d'utiliser la distorsion optique des ondes lumineuses traversant un œuf placé sous un microscope, d'envoyer ces données à un PC qui analyse les informations reçues et détermine la position de la fusée mitotique. 

    Avec les informations concernant l'absence ou la présence du fuseau de division dans l'ovocyte, sa localisation et sa clarté, il est possible de faire des prédictions sur la qualité de l'œuf. La visualisation de la fusée minimise la probabilité de dommages à ICSI/IMSI et augmente ainsi l'efficacité de la fécondation et la qualité des embryons. 

    De plus, les informations obtenues grâce à cette procédure peuvent répondre à un certain nombre de questions concernant les causes d'une mauvaise fécondation et la faible qualité des embryons dans les programmes précédents.

La Clinique Altravita occupe des positions de leader dans le domaine de la médecine reproductive, du traitement de l'infertilité féminine et masculine, des études cytogénétiques et moléculaires-génétiques.

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